Drugs

EP-lab drug reference.

Indication, typical dose, kinetics, monitoring, and reversal — in a quick-reference format.

Anticoagulants

Heparin (IV, intra-procedural)

Workhorse anticoagulant for left-heart and transseptal cases. Bolus by weight, follow ACTs, redose to stay in window.

Antiarrhythmics

Adenosine

Fast-on, fast-off AV-nodal blocker. Diagnostic for SVT, used to unmask dormant PV conduction, and to test accessory pathways.

Amiodarone IV

Broad-spectrum antiarrhythmic for VT, recurrent AF, and rhythm control in the EP lab. Effective but slow-loading and full of late effects to remember.

Sedation & anesthesia

Midazolam + Fentanyl (Moderate Sedation)

Our standard nurse-administered sedation combo for device implants, EP studies, and most right-sided ablations. Titrate to comfort, not to a number.

Propofol (Anesthesia Cart)

Anesthesia-administered IV agent for deep sedation and general anesthesia in the EP lab. Fast on, fast off, but narrow safety window — not nurse-pushed.

Reversal agents

Protamine Sulfate

Heparin reversal agent. Used selectively at the end of left-heart cases or for bleeding — pushed slowly to avoid hypotension.

Vasoactive / resuscitation

Atropine

Anticholinergic for vagally-mediated bradycardia and AV block. Crash-cart staple, used reactively in EP for vagal reactions during sheath placement and ablation.

Isoproterenol (Isuprel)

Non-selective beta-agonist we use to provoke arrhythmias, unmask dormant PV conduction, and tease out latent triggers.