Indications
- Symptomatic recurrent SVT of any mechanism in patients preferring definitive therapy over chronic drugs
- Symptomatic Wolff-Parkinson-White
- High-risk asymptomatic WPW — short pre-excited RR in AF, multiple pathways, athletes
- Incessant atrial tachycardia causing tachycardia-induced cardiomyopathy
- Drug intolerance or failure
Pre-procedure prep
- Anticoagulation not required for right-sided ablations; therapeutic for left-sided cases or LA mapping
- NPO after midnight
- AV nodal blockers held for 24–48 hours pre-procedure to facilitate induction
- Baseline 12-lead ECG including any documentation of pre-excitation
- Sedation plan: moderate sedation is standard; deep sedation can suppress inducibility — coordinate with anesthesia
Setup & equipment
- Three right femoral venous accesses: His, CS, ablation
- Some operators use an additional RV catheter for ventricular pacing maneuvers
- Heparin only for left-sided work
- Programmed stimulator ready for atrial and ventricular pacing protocols
Technique
Baseline EP study
- Sinus rhythm assessment: AH and HV intervals, presence of pre-excitation
- Atrial pacing protocols: incremental and extrastimulus to assess AV node and pathway conduction
- Ventricular pacing: VA conduction time, retrograde activation pattern (concentric vs eccentric)
- Tachycardia induction: burst and extrastimulus pacing, plus isoproterenol if needed
Diagnostic maneuvers
- AVNRT signature: dual AV node physiology (AH jump), septal earliest A on tachycardia, VA time <70 ms, V-A-V response after RV overdrive
- Orthodromic AVRT signature: eccentric retrograde A (location depends on pathway), VA >70 ms, V-A-V response, para-Hisian pacing showing pathway behavior
- AT signature: V-A-A-V response after RV overdrive, variable AV relationship possible, P morphology distinct from sinus
- Concealed pathway: VA time during ventricular pacing constant with rate; AV node decremental
Ablation strategy
AVNRT — slow pathway modification
- Target the slow pathway anatomically: posterior-inferior septal RA, between the tricuspid annulus and CS os
- Look for slow pathway potential (small atrial deflection followed by larger ventricular)
- RF at 25–40 W; cryoablation 4–6 mm tip catheter is an alternative with lower AV block risk
- Watch for junctional rhythm during ablation — desired endpoint, but monitor VA conduction; loss of VA = stop immediately
- Endpoint: non-inducibility on and off isoproterenol, with elimination of slow pathway or single residual echo beat acceptable
AVRT — accessory pathway ablation
- Right-sided pathways: ablate from the RA at the tricuspid annulus, mapped by earliest delta wave (manifest) or earliest atrial activation (concealed)
- Left-sided pathways: retrograde aortic approach to the mitral annulus, or transseptal approach
- Mid-septal and parahisian pathways: high risk for AV block — consider cryoablation
- Map carefully for shortest AV time on the annulus
- RF at the target; success often within seconds of starting if mapping is correct
Focal AT
- Activation mapping during tachycardia identifies the earliest atrial site
- 3D mapping invaluable, especially for non-PV foci
- Target the focus; success indicated by termination during energy delivery and non-inducibility
Confirming cure
- Wait 20–30 minutes after ablation
- Repeat induction protocols with and without isoproterenol
- For AVNRT: residual slow pathway conduction without inducibility is acceptable
- For AVRT: complete pathway block (no conduction antegrade or retrograde) is the goal
- For AT: non-inducibility and absence of spontaneous foci
Complications
- AV block requiring permanent pacing: <1% overall, higher for septal pathways and aggressive slow pathway ablation
- Vascular complications: ~1%
- Tamponade: rare, more likely with transseptal or aggressive ablation near the annulus
- Stroke: rare, mainly with left-sided work
- Recurrence: 3–5% for AVNRT, 5–10% for AVRT depending on location
Post-procedure care
- Bed rest 2–3 hours, then ambulate
- Same-day discharge for uncomplicated cases
- Anticoagulation for 4 weeks after left-sided ablation; not needed for right-sided
- Follow-up at 4–6 weeks; counsel patients that occasional palpitations during the first few weeks are common and don’t necessarily indicate failure
- Antiarrhythmics typically discontinued at discharge